KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
H2AFX
All Species:
9.09
Human Site:
T124
Identified Species:
18.18
UniProt:
P16104
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P16104
NP_002096.1
143
15145
T124
L
P
K
K
T
S
A
T
V
G
P
K
A
P
S
Chimpanzee
Pan troglodytes
XP_520760
155
16635
C124
L
P
K
K
T
E
I
C
E
H
S
G
P
S
S
Rhesus Macaque
Macaca mulatta
XP_001090149
155
16475
C124
L
P
K
K
T
E
I
C
G
H
S
G
P
S
S
Dog
Lupus familis
XP_853256
242
25674
T223
L
P
K
K
T
S
A
T
V
G
P
K
A
P
A
Cat
Felis silvestris
Mouse
Mus musculus
P27661
143
15124
T124
L
P
K
K
S
S
A
T
V
G
P
K
A
P
A
Rat
Rattus norvegicus
P02262
130
14059
I112
Q
G
G
V
L
P
N
I
Q
A
V
L
L
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512371
142
15010
A124
L
P
K
K
S
G
A
A
S
S
P
K
A
P
N
Chicken
Gallus gallus
P02263
129
13922
N111
A
Q
G
G
V
L
P
N
I
Q
A
V
L
L
P
Frog
Xenopus laevis
Q6GM86
139
14837
K120
Q
A
V
L
L
P
K
K
S
S
G
G
V
S
T
Zebra Danio
Brachydanio rerio
Q7ZUY3
142
14983
A124
L
P
K
K
T
G
Q
A
A
A
S
S
G
K
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P84051
124
13344
G105
S
G
V
T
I
A
Q
G
G
V
L
P
N
I
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
P16886
126
13432
V108
V
T
I
A
Q
G
G
V
L
P
N
I
Q
A
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
79.3
79.3
58.6
N.A.
97.1
85.3
N.A.
93
85.3
84.6
87.4
N.A.
79
N.A.
N.A.
81.8
Protein Similarity:
100
81.2
81.9
59
N.A.
99.3
86.7
N.A.
94.4
86.7
90.2
90.2
N.A.
83.2
N.A.
N.A.
84.6
P-Site Identity:
100
40
40
93.3
N.A.
86.6
6.6
N.A.
60
0
0
40
N.A.
0
N.A.
N.A.
0
P-Site Similarity:
100
40
40
100
N.A.
100
6.6
N.A.
73.3
6.6
6.6
40
N.A.
6.6
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
9
0
9
0
9
34
17
9
17
9
0
34
9
17
% A
% Cys:
0
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
17
0
0
9
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
17
17
9
0
25
9
9
17
25
9
25
9
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
17
0
0
0
0
0
% H
% Ile:
0
0
9
0
9
0
17
9
9
0
0
9
0
9
0
% I
% Lys:
0
0
59
59
0
0
9
9
0
0
0
34
0
9
9
% K
% Leu:
59
0
0
9
17
9
0
0
9
0
9
9
17
9
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
9
9
0
0
9
0
9
0
9
% N
% Pro:
0
59
0
0
0
17
9
0
0
9
34
9
17
42
9
% P
% Gln:
17
9
0
0
9
0
17
0
9
9
0
0
9
0
9
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
9
0
0
0
17
25
0
0
17
17
25
9
0
25
34
% S
% Thr:
0
9
0
9
42
0
0
25
0
0
0
0
0
0
9
% T
% Val:
9
0
17
9
9
0
0
9
25
9
9
9
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _